The state of the population of intestinal stem cells depends on the regularity of updates of the cells lining the intestinal tract. The authors of this study found that with age, the capacity for production among intestinal stem cells weakens, and with this process the increased risk of developing age-related gastrointestinal diseases correlates. But it was possible to restore the performance of stem intestinal cells in the old organism and thereby overcome the painful processes. During experiments with mice, scientists found that the compound nicotinamide riboside copes with this task.
Experiments have shown that after six weeks of consumption of nicotinamide riboside, due to its effect, the population of stem cells in the intestines of old animals increased and began to synthesize organelles similar to the way it occurs in a young organism. Scientists attribute this effect to the ability of a substance to inhibit inflammation.
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Thus, experts believe, the effect on intestinal stem cells, contributing to the resumption of their growth and the fight against inflammation, can be the basis for methods of preventing aging.